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Drug ReportsAluminum hydroxide
Aluminum hydroxide
Dibasic, Monobasic, Monohydrate, Phosphate (aluminum hydroxide) is a small molecule pharmaceutical. Aluminum hydroxide was first approved as Sodium phosphates in plastic container on 1983-05-10. It is used to treat duodenal ulcer, dyspepsia, gastroesophageal reflux, gastrointestinal hemorrhage, and heartburn amongst others in the USA.
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Therapeutic Areas
Therapeutic Area
MeSH
digestive system diseasesD004066
signs and symptoms pathological conditionsD013568
Trade Name
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Drug Products
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Abbreviated New Drug Application (ANDA)
Aluminum hydroxide
+
Magnesium trisilicate
Tradename
Company
Number
Date
Products
GAVISCONSanofiN-018685 DISCN1983-12-09
2 products, RLD
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FDA Information
Sodium Phosphate, Dibasic, Anhydrous / Sodium Phosphate, Monobasic, Monohydrate, Osmoprep, Salix Pharms
76870752028-06-22DS, DP
ATC Codes
A: Alimentary tract and metabolism drugs
— A02: Drugs for acid related disorders
— A02A: Antacids
— A02AB: Antacids containing aluminium compounds
— A02AB01: Aluminium hydroxide
HCPCS
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Clinical
Clinical Trials
403 clinical trials
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Indications Phases 4
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Indications Phases 3
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Indications Phases 2
Indication
MeSH
Ontology
ICD-10
Ph 1
Ph 2
Ph 3
Ph 4
Other
Total
Healthy volunteers/patients———11———2
Tobacco use disorderD014029—F17—1———1
Indications Phases 1
Indication
MeSH
Ontology
ICD-10
Ph 1
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Total
Streptococcus agalactiaeD013292NCBITaxon_1311—1————1
Indications Without Phase
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Epidemiology
Epidemiological information for investigational and approved indications
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Drug
General
Drug common nameAluminum hydroxide
INN—
Description
Aluminium hydroxide, Al(OH)3, is found in nature as the mineral gibbsite (also known as hydrargillite) and its three much rarer polymorphs: bayerite, doyleite, and nordstrandite. Aluminium hydroxide is amphoteric, i.e., it has both basic and acidic properties. Closely related are aluminium oxide hydroxide, AlO(OH), and aluminium oxide or alumina (Al2O3), the latter of which is also amphoteric. These compounds together are the major components of the aluminium ore bauxite. Aluminium hydroxide also forms a gelatinous precipitate in water.
Classification
Small molecule
Drug class—
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Structure (InChI/SMILES or Protein Sequence)
O[Al](O)O
Identifiers
PDB—
CAS-ID21645-51-2
RxCUI—
ChEMBL IDCHEMBL1200706
ChEBI ID33130
PubChem CID10176082
DrugBankDB06723
UNII ID—
Target
No data
Variants
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Estimated US medical usage
Aluminum hydroxide
Total medical expenditures per year (USD, in millions)
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Safety
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1,845 adverse events reported
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